I am guessing you are referring to Claudius' speech in Act III, Scene III and if so, this monologue gives us an idea that Claudius feels strongly about the possibility of consequences for his murderous actions.
He questions whether or not there is enough forgiveness out there to wash away the blood of his murder of his brother by wondering if there is enough rain in the "sweet heavens" to wash it white again.
He wonders if there is some form of prayer that can be used to obtain forgiveness for his terrible actions and how might he avail himself of that power.